England coach Stuart Lancaster has had to drop Billy Vunipola and replace the number eight with Thomas Waldrom in his squad for the November test finale  against Australia on Saturday because of concussion.
Vunipola took a blow to the head in Saracens' 31-24 Premiership defeat by Northampton on Sunday and has been ruled out of contention for Twickenham against the Wallabies.
He was dropped for the 28-9 victory over Samoa at Twickenham at the weekend - Ben Morgan started in his place - and was unlikely to figure in the climax to the autumn.
"Billy will undergo the graduated return to play protocol at his club," read a statement released by England.
Saturday's win over Samoa ended a run of five straight defeats for the 2015 World Cup hosts.
Australia, their pool rivals in the World Cup, went down 29-26 to Ireland in Dublin in their weekend test in Dublin.
While Waldrom is not expected to feature against Australia, his inclusion among the 34 players called up to England's Pennyhill Park training camp is reward for the strong form shown for second-placed Exeter.
Fly-half Stephen Myler is in the squad after recovering from a hamstring strain, while his Saints team-mate Courtney Lawes is being treated for a knee injury that could sideline him for the visit of the Wallabies.
If Lawes fails to recover in time, Dave Attwood and George Kruis will start with Graham Kitchener offering cover from the bench.
Source: AFP