Iranian researchers produced and studied a biosensor with the capability of measuring biological indices of heart diseases and disorders.

The potential of these diseases and heart attack can be predicted by using the sensor. Results of the research have applications in medical and clinical studies, and in pathology laboratories.

A biosensor has been designed in this research that enables the prediction of heart diseases by measuring CCP and CRP indices. The sensor evaluates the concentration of CCP and CRP biological indices – which are the cause of heart diseases in humans – and it predicts the potential of the diseases at any age by measuring the level of the indices. In fact, the normal and allowed level of the indices has been defined for each age, and the sensor detects the risk of the heart disease when the value of the index goes higher than the allowed value.

According to the researchers, the proposed sensor is able to measure the indices with high accuracy and sensitivity. The detection limit of the sensor is at nanomolar scale, and it is able to detect the indices in human blood serum without causing any troubles. The sensors can be produced through a simple, fast, and cost-effective method, and they can be used for a few months.

The research team is working on the production of detection biosensors to diagnosis other diseases, including thyroid and prostate cancers and other common types of cancers, and the results will be published in future.

Results of the research have been published in Biosensors and Bioelectronics, vol. 63, issue 1, 2015, pp. 490-498.